Vaccines can be delivered through the skin using ultrasound. This method doesn’t damage the skin and eliminates the need for painful needles. To create a needle-free vaccine, Darcy Dunn-Lawless at the University of Oxford and his colleagues mixed vaccine molecules with tiny, cup-shaped proteins. They then applied liquid mixture to the skin of mice and exposed it to ultrasound – like that used for sonograms – for about a minute and a half.

  • tsonfeir@lemm.eeOP
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    Antivaxxers now pro-abortion to avoid forced ultrasound vaccinations.

    • FarFarAway@startrek.website
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      As interesting as that would be to happen, in reality, there’s just going to be a bunch more people going without pre natal care.

      • tsonfeir@lemm.eeOP
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        Which is going to be most red states in the next decade. Great time to be in the little coffin business though.

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    While this is awesome, I can already imagine anti-vaxxers are now deathly afraid of ultrasounds lol

    • coffeebiscuit@lemmy.world
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      Brace yourselves! Vaccination with sound conspiracies coming in!

      “The IRS called, they vaccinated me trough my phone in my ear!!?”

      “Mass vaccinations trough radio!!?”

    • Blackmist@feddit.uk
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      They were already terrified of phone signals.

      Only fast ones though. Slower ones can’t penetrate the skin.

      • PsychedSy@sh.itjust.works
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        7 months ago

        Hilariously enough, it’s closer to the other way 'round. Higher frequencies means more bandwidth but they can be blocked easier. Lower frequencies can go farther before being attenuated too much.

        • pete_the_cat@lemmy.world
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          One of my friend’s friends has a PhD in psychology, but she thinks that nuclear radiation has healing properties and told me to move out of NYC because there was too much 5G everywhere. She still uses a smartphone though, just on a selfie stick on speakerphone 🤣 She also told me that she was afraid of the radio in her car because of the radio waves.

          • 0000011110110111i@lemm.ee
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            She thinks that nuclear radiation has healing properties

            In a way she’s actually not wrong. That’s what radiotherapy is. Focused nuclear radiation to heal cancer.

            • pete_the_cat@lemmy.world
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              She doesn’t have cancer though, she’s perfectly healthy and is an “alternative medicine practitioner”. She said she sleeps with a piece of thorium under her pillow.

              Regardless of it being used for cancer treatment, nuclear radiation isn’t good for the body in any way. Various forms of radiation (not just nuclear) are harmful, like getting too much sun.

                • pete_the_cat@lemmy.world
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                  6 months ago

                  I’m convinced that she’s just nuts. My friend, who is her friend (how I met this woman), told me that the woman has started “Urine Therapy” and I just said “Jesus fucking Christ… I… I just have nothing to say” because I didn’t wanna get into a debate with him about it.

    • Syndic@feddit.de
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      Wanna bet that they will somehow combine this with 5G conspiracies?

      “It’s all just a wave after all!!!” /s

    • silly goose meekah@lemmy.world
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      Idk, anti vaxxers aren’t afraid of needles/syringes as far as I understand. They don’t want that kind of substance to be put inside their body, regardless of the method of administration

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        I mean, yes, but a lot of them also think it’s a conspiracy where world leaders are trying to vaccinate everyone because ??? Those types will start avoiding ultrasound to not get tricked into getting vaccinated.

        • pete_the_cat@lemmy.world
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          The best part is “depopulation by helping people stay healthy” e.g. The Bill and Melinda Gates Foundation.

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        It’s too bad we can’t put vaccines in cum. We’d either have nearly 100% vaccine rates or the antivaxxers would quickly die out.

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    I think that’s the basic premise of the Star Trek hypospray. Pressure pushing in medicine rather than a needle.

    • Dkarma@lemmy.world
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      I was gonna say oh now they are gonna say that’s what the 5g towers are REALLY for 🙄🙄🙄

      • Ultraviolet@lemmy.world
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        At this point if it was possible to orchestrate some massive conspiracy to vaccinate people en masse, we should just do that. They’ll shout about it either way, but this way they’ll at least be vaccinated

        • turmacar@lemmy.world
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          This is basically the fluoride ‘debate’.

          (Yes, fluoridating the water supply is good.)

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            I specifically remember my bio mom ranting about how we all would have telekinetic powers if not for the fluoride in the water. She believed that was the ‘real’ reason the government did it.

          • RickyRigatoni@lemmy.ml
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            Also, if you are injesting enough flouride to cause health issues when you brush your teeth, you are brushing horrifically wrong.

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      That was my first thought the flat earthers and mud flood people are going to have a field day with this!

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      No joke. The first thing that popped into my mind when reading the title was: “great, now my father will be afraid to do an ultrasound test”

    • AlternateMrPapaya@lemmy.world
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      Finally? They were used back in the 1970s. There were issues with them getting contaminated during use, so disposable needles became the norm.

  • sndmn@lemmy.ca
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    7 months ago

    I should patent a long range dart gun for vaccinating morons.

  • MeatPilot@lemmy.world
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    History proves we do the cheapest, easiest, and fastest. So allow me to shit all over this idea…

    • This is slow at 1.5 mins vs a needle takes about 5 secs.
    • Takes skill to operate an ultrasound machine and probably training to get a consistent dose vs pull needle to this line and jab in arm to know you got it all in there.
    • Every Rite Aid and CVS would need an ultrasound machine vs here are these cheap disposable needles that require no power or maintenance.

    Sure they might develop it faster or make a new more portable thing. But that’s going to take a long long time when no one gives a shit to invest money in a new thing when needles work.

    • Mereo@lemmy.ca
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      As with all new inventions/procedures, this is just the first step. The process will become faster and more efficient in the future.

      In my opinion, this is a great first step towards a Star Trek-like hypospray.

    • KairuByte@lemmy.dbzer0.com
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      No one is suggesting this be put in practice in its current form, that would be insane. That said, this is a good first step for alternative forms of vaccination. “First step” being the important part.

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      Might be useful for those people whose blood doesn’t clot. Though I don’t know if a small syringe needle is even an issue for them anyway

    • scarabic@lemmy.world
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      A machine that produces ultrasonic waves is not that complex. It’s the sensors and qualified technician to read and capture the scans that’s expensive.

      Plus have you ever had to physically restrain your child through a needle shot? You said “easiest” and that shit ain’t easy.

      • SacralPlexus@lemmy.world
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        You seem to be the only commenter here who recognizes that this would be amazing for pediatric patients - who coincidentally receive way more vaccines than adults.

    • Neato@kbin.social
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      • 1.5min really isn’t that long compared to the procedures just to process insurance, identity, etc. Retrieving needles, etc. This only needs the topical vaccine, an ultrasound machine, and a wipe for the machine.
      • When this goes mainstream it’ll be a little device with cutout so you can apply it flawlessly to the upper arm. Ultrasounds need training to get readable data, but probably a LOT less just to apply ultrasound to an area.
      • Needles will still be king anywhere in the developing world. It’ll be more expensive initially, but with the mass production the price will go down. And there will be small cost savings to not having to deal with sharps and biohazards as often.
    • verysoft@kbin.social
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      I’d like to be an optimist when it comes to things like this, some people really really can’t stand needles and something like this would be great for them people. I hope it develops further.

  • Joshua Hershey@lemm.ee
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    We are one step closer to hypo sprays from Star Trek. I don’t like needles so this will be really neat to see in mass adoption.

    • Blue_Morpho@lemmy.world
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      Hyposprays already were invented, mass produced, used as standard in the military for several years, and abandoned because they weren’t as hygienic as needles.

      Anything that pushes through the skin into the blood pushes pathogens in too. Statistically, needles were safer so hyposprays were abandoned.

      • lolcatnip@reddthat.com
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        Presumably the version they use in Star Trek avoids that problem somehow, so it’s still a thing that would need to be invented.

        • FordBeeblebrox@lemmy.world
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          The doctors are constantly jabbing people one right after another and often through the uniform…I’d love to see the explanation in universe for that

          • Blue_Morpho@lemmy.world
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            Medicine is improved so everyone has super immunity in the future. So it’s not that the hypo isn’t pushing dirt into their veins, it’s that they don’t care.

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    Sitting for a minute and a half, not including prep and cleanup, or just getting stabbed a little. shrug

    Edit: To save the next half dozen people exclaiming “needles!” the trouble. I would refine my point to, “great to have the option but I imagine it as being more of a fallback than the beginning of a new era”.

    • Ultraviolet@lemmy.world
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      Needle phobias are extremely common, and the thing about phobias is that you’re fully aware that the fear isn’t coming from a rational place, which is part of what makes them so frustrating to deal with.

      • Emerald@lemmy.world
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        the thing about phobias is that you’re fully aware that the fear isn’t coming from a rational place

        Lol yeah when I get vaccinated the anxiety fully fades the moment the needle enters my arm.

    • DBT@lemmy.world
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      I’ll take it over having a sore arm for a day or two.

      Getting a shot isn’t a big deal, but neither is sitting for five minutes.

    • mechoman444@lemmy.world
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      It’s not just the time we’ve saved here. Think of people on insulin that have to take shots multiple times a day.

      The medical implications of this are massive it is absolutely a game changer.

      If it ever comes into fruition.

      • Chaotic Entropy@feddit.uk
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        We’ll have to wait and see how this impacts anything that needs to be injected deeper than skin level, which is why the focus is on vaccines.

    • ItsMeSpez@lemmy.world
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      It’s certainly less time effective if administering vaccines to large populations at once, but the increased antibody generation could absolutely make it worth it. Don’t know much about these things, but could mean the difference between two jabs and one 1.5 minute appointment.

    • Nathanator@lemmy.world
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      Maybe one way of looking at it might be : this would be safe enough you could trust people to self-administer, and you could therefore take the professional with the needle out of the equation.

      90 seconds of one person’s time has got to be better than the quick jab by two people, no?

      • Chaotic Entropy@feddit.uk
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        Depending on how specific the injection needs to be, there are a number of scenarios in which people can self-administer injections. So, ignoring people who physically can’t self-administer, it isn’t that dramatic a change.

        I can’t help but feel that the professional would be even more necessary to administer this correctly and not just waste a treatment/dose doing it wrong, whilst under the illusion that you did it right. Along with the specialised equipment needed for it in the first place. Needles and doses at least are pretty easily self-contained and if it is suitable for self application just “pointy end goes in fat bit of you”.

        Naturally it’s early days, so it’ll be fascinating to see how this develops.

        • Nathanator@lemmy.world
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          I agree! Auto injectors aren’t cheap compared to ye olde trusty ampule and syringe, and this might push the costs towards the higher end again. I can see a kids-and-the-latex-allergic edge case scenario.

          Can’t wait to see what develops 😄

      • Ech@lemm.ee
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        I don’t think any amount of de-specializing would be enough to trust the ignorant and/or malicious masses could or would self-administer adequately.

        • Nathanator@lemmy.world
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          You’re right. Can’t just post them to folks and expect 100% uptake. It might widen the possibilities of more people getting more vaccines, though. In my books, this can only be a good thing.

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    If they can do this for insulin which sounds like it’s the same this is a game changer