• Dudewitbow@lemmy.zip
    link
    fedilink
    English
    arrow-up
    61
    ·
    5 months ago

    Reading the article, kinda happy that different countries are working on different cancer fighting mrna options that currently are on different phases.

  • AlmightyDoorman@kbin.earth
    link
    fedilink
    arrow-up
    40
    ·
    5 months ago

    Can’t read the whole article due to paywall. Here are 2 thoughts for the half that i did read.

    • colorectal cancer makes a lot of sense as a target. it still is one of the most cancers with the highest mortality. At the same time we saw an uptick in colorectal cancer rates in young people (reason unknown, maybe microplastics maybe something else.). Furthemore colorectal cancer seems to be a great target for immunsystem modulating therapy. There was a paper 3 years bake in I think the NEJM where they put 18/18 (exact N not sure) patients in remission with PD-1 modulation which also activates the immun system.

    • Astra Zeneca (I believe) is also working on a mRNA vaccine for cancer that is quite far along. They are targeting melanoma in remission and reduced reoccurence of melanoma or metastasis after 3 years by 50%. So it seems like mRNA cancer vaccines will be a strong pillar for future cancer treatements.

    Sadly we saw in the past that russia sometimes bolsters their numbers for medication efficency. I hope it is not the case this time but i hope that the phase 2/3 trials will be very transparent to quench any doubts.

    • Guidy@lemmy.world
      link
      fedilink
      English
      arrow-up
      8
      ·
      5 months ago

      Eh if they come up with a reliable way to defeat it I’d say it’s worth it.