Whether you are doing prescribed HRT or have resorted to DIY, this guide might be helpful to those of you who will be taking injections. It contains a bunch of links and I explain some terms that I don’t always see explained elsewhere.
This guide should be applicable to transmascs as well as transfems, but some tools and links are unfortunately focused on feminizing HRT.
Also, I would very much like feedback on this guide and more resources and guides to link.
Helpful links
- Check here and here for some good info and guidelines on dosages for transfems.
- There is also this estradiol simulator, however be aware that everyone is different and that the simulator only shows the expected average (actual values can vary a lot between individuals).
Guides
Here are some guides written by people with more experience than me.
- https://transharmreduction.org/injecting-safely
- https://www.transcarebc.ca/hormone-therapy/injecting-hormones
- https://0x2640.estrogen.productions/ic33b9es.pdf (despite the host name this guide is for both transmascs and transfems)
- Intramuscular video guide
- Sub-q video guide
What is IM/intramuscular and sub-q/subcutaneous?
Subcutaneous is an injection into the fat below your skin. Some people experience that their skin reacts to the liquid you inject when doing this kind of injection, and some don’t (resulting in a sore red bump at the injection site).
Instramuscular is a deeper injection into your muscles. This is the one your doctor will recommend to you as you are way less likely to have a reaction with this one than with sub-q.
Both give you the same results. Both will give you approximately the same amount of hormones. Pick whichever you are most comfortable with.
What does “gauge” mean?
For us gauge is a measurement of how thin a needle is. The higher the gauge, the thinner the needle, with 30G being very thin and 15G being thicker.
Generally you can use a wide range of gauges for HRT. A higher gauge will be kinder on the rubber stopper and have less chance to cause coring in the long run, while a smaller gauge will draw the liquid out quicker and do better with thicker oils.
I use a 29G insulin needle myself.
What needle should I use?
Needle gauge
Appropriate gauges (needle thickness) for a subcutaneous injection are 25-30g, for intramuscular, 23-25g. Subq needles are thinner than IM needles, which some people find less intimidating.
From the diyhrt website.
Needle length
Recommended needle lengths are as follows: 1”-1 ½” (IM, 1 inch is better for thinner people and 1 ½” for thicker people) ½”-⅝” (Subq, up to personal preference)
From the diyhrt website. 1 inch is about 25 mm.
Size of the syringe
Your syringe should be a 1 ml syringe if possible (makes it easier to get a more precise dosage).
Addressing concerns
Accidentally injecting into a vein
If you are injecting into the recommended areas you will not be hitting any large veins, nor are the effects of accidentally injecting into a vein all that troublesome, even if you inject a bit of air. Your shot is mostly wasted if you do manage to inject into a vein (which is very unlikely). Some people recommend aspirating to avoid this happening (pull the needle back a bit after sticking the needle in but before injecting. If you see blood then replace the needle and try again), but it’s not strictly necessary.
Missing a day, doing an injection a day early
This is usually fine for most types of hormone injections. Resume your regular schedule.
I injected too much
If you injected something like twice as much as needed then just continue taking shots at a regular interval. If you injected something like 10 times as much as needed you might feel some discomfort during the next month, but nothing you can’t handle. Just wait three or four weeks and continue like normal after that. Doing this accidentally isn’t an issue, even if not recommended.
I injected too little
If you were off by some tiny margin then you likely won’t even notice on a blood test that you were off. If you were off by something like half or more then maybe try another injection, but with a smaller dose. Don’t do another full injection.
Nervousness
It’s okay if you struggle with your injection. It’s okay if you’re nervous and shaky. It’s okay if you can’t do it. Maybe you can have someone there with you, be it physically or over voice. Maybe you just need to try again some other day when you are in a different state of mind.
Things to keep in mind
If some blood comes out, that’s fine. If some other liquid comes out, that’s also fine. Maybe have some paper or bandaids handy in case you tend to bleed after your injections. Don’t inject into the same area each time, instead rotate between a few areas to avoid buildup of scar tissue.
It’s okay. You did good <3
Even if you messed up a few times, wasted some ester or syringes, or you injected a bit too much or too little, it’s okay, don’t worry.
This seems pretty dangerous no?
Not at all! it might seem complicated, but it’s all fairly straight forward and safe
Edit: I should also say for many of us HRT is life changing or even life saving, but is unfortunately not as accessible as it should be