A loophole in FDA processes means older drugs like the ones in oral decongestants weren’t properly tested. Here’s how we learned the most popular one doesn’t work
Nasal means nose. Your sinuses are not your nose. Not sure why this is difficult? You’ve posted a second link to its use as a nasal decongestant.
“MEDLINE, the Cochrane Central Registry of Controlled Trials, EMBASE, International Pharmaceutical Abstracts, and the Federal Register were searched for English and non-English-language studies published through January 2007 that measured the effects of oral phenylephrine on nasal airway resistance (NAR) in patients with nasal congestion.”
Again, you’re making a distinction where there is none, we are talking about the same thing. So you’ll never find a study with the specific term you want, because that’s not the term used for that symptom in research.Your sinuses are a part of your nasal passage and nasal airway (nasal doesn’t just mean, literally in the nose in the front of your face and nowhere else in this context, it’s referring to the whole cavity), decongestants consrict blood vessels to shrink the size of tissues and to reduce production of mucus. There’s no such thing as an over the counter medication with a specific indication of “sinus congestion” versus “nasal congestion.” Phenylephrine never carried any special label as a “sinus” decongestant, that’s not an actual distinction anyone makes, it’s the same tissue. It’s like you’re saying “sure you have all these studies about global warming, but I was asking about climate change,” like yes, these refer to the same phenomenon.
Like here’s a label if you don’t believe me:
Look at the box of active ingredients: it says nasal decongestant (not sinus decongestant) is the indication. It refers to your whole nasal airway, including sinuses. That’s why under uses afterward it specifically mentions sinus pressure/symptoms. Nasal decongestant refers to relieving that symptom. This is my last comment on this chain because I don’t know what else to tell you. You’re misinterpreting terms here. And if you still don’t believe me, if the nasal decongestant indication didn’t refer to relieving sinus pressure, it would literally be illegal for it to be labeled this way, as drugs cannot be labeled for a non-FDA approved indication. But don’t worry there’s still plenty of alternative decongestants that do have actual evidence that can be used.
This is a whole “Shit Americans Say” conversation. I understand that you are struggling with the idea that meds can be used for other reasons, reasons that may not be allowed in your country.
However the headline saying a medication doesn’t work is false.
You have linked studies about breathing, do you breathe through your sinuses?
Nasal means nose. Your sinuses are not your nose. Not sure why this is difficult? You’ve posted a second link to its use as a nasal decongestant.
“MEDLINE, the Cochrane Central Registry of Controlled Trials, EMBASE, International Pharmaceutical Abstracts, and the Federal Register were searched for English and non-English-language studies published through January 2007 that measured the effects of oral phenylephrine on nasal airway resistance (NAR) in patients with nasal congestion.”
Again, you’re making a distinction where there is none, we are talking about the same thing. So you’ll never find a study with the specific term you want, because that’s not the term used for that symptom in research.Your sinuses are a part of your nasal passage and nasal airway (nasal doesn’t just mean, literally in the nose in the front of your face and nowhere else in this context, it’s referring to the whole cavity), decongestants consrict blood vessels to shrink the size of tissues and to reduce production of mucus. There’s no such thing as an over the counter medication with a specific indication of “sinus congestion” versus “nasal congestion.” Phenylephrine never carried any special label as a “sinus” decongestant, that’s not an actual distinction anyone makes, it’s the same tissue. It’s like you’re saying “sure you have all these studies about global warming, but I was asking about climate change,” like yes, these refer to the same phenomenon.
Like here’s a label if you don’t believe me:
Look at the box of active ingredients: it says nasal decongestant (not sinus decongestant) is the indication. It refers to your whole nasal airway, including sinuses. That’s why under uses afterward it specifically mentions sinus pressure/symptoms. Nasal decongestant refers to relieving that symptom. This is my last comment on this chain because I don’t know what else to tell you. You’re misinterpreting terms here. And if you still don’t believe me, if the nasal decongestant indication didn’t refer to relieving sinus pressure, it would literally be illegal for it to be labeled this way, as drugs cannot be labeled for a non-FDA approved indication. But don’t worry there’s still plenty of alternative decongestants that do have actual evidence that can be used.
This is a whole “Shit Americans Say” conversation. I understand that you are struggling with the idea that meds can be used for other reasons, reasons that may not be allowed in your country.
However the headline saying a medication doesn’t work is false.
You have linked studies about breathing, do you breathe through your sinuses?
https://www.saintlukeskc.org/health-library/understanding-nasal-anatomy-inside-view
Here is a diagram to help, it labels the nasal cavity and the sinuses which it shows you are air filled chambers around your nose.
Are you brain damaged or something?
Took too much phenylephrine 😔