cross-posted from: https://lemmy.world/post/8180477

Why this is significant: There is no currently known treatment to stop suicidal thoughts when they happen. Antidepressants take 4-6 weeks to start working, and they don’t work for everyone. Therapy also takes time. Our best option for acutely suicidal people is to lock them up in a psychiatric facility until they are no longer a threat to themselves.

Intravenous ketamine offers a glimpse of hope. A single dose appears able to alleviate suicidal ideation immediately after administration and for up to a week afterwards.

  • sky@codesink.io
    link
    fedilink
    English
    arrow-up
    14
    ·
    1 year ago

    My therapist recommended this for me, or esketamine which my insurance may cover, but my doctor thought trying a regular antidepressant first was best, despite having tried many before.

    I am doing better than I was, for sure, but I do wonder if I could be even better. I’m also honestly lucky to have made it through the dark period before the meds kicked in.

    • ickplant@lemmy.worldOP
      link
      fedilink
      English
      arrow-up
      3
      ·
      1 year ago

      I’m glad you made it through that dark period. Is your doctor no longer willing to consider esketamine since the antidepressant is sort of working? That’s too bad, if so. I know insurance can be picky with what they cover, too. I have a lot of hope that all of this will improve as psychedelic treatment for depression becomes more and more commonplace. For now, give us a follow at Psychedelic Therapy, and see if your doctor changes their mind!

  • intensely_human@lemm.ee
    link
    fedilink
    English
    arrow-up
    4
    arrow-down
    6
    ·
    1 year ago

    A single dose of IV ketamine is generally quite expensive.

    If the effects last a week, might not be worth it

      • Chozo@kbin.social
        link
        fedilink
        arrow-up
        11
        arrow-down
        2
        ·
        1 year ago

        Unfortunately, those are the options most Americans have. Either pay more than you can afford to fix it or let it kill you.

        • 👁️👄👁️@lemm.ee
          link
          fedilink
          English
          arrow-up
          3
          arrow-down
          8
          ·
          1 year ago

          Uh there are a lot of anti depressants out there. I pay $15/mo for mine. This is just misinfo and xenophobia.

            • 👁️👄👁️@lemm.ee
              link
              fedilink
              English
              arrow-up
              2
              ·
              1 year ago

              Anything that isn’t “any health care = bankrupt” disrupts their circle jerk lol. They don’t actually know how reality works here.

    • ickplant@lemmy.worldOP
      link
      fedilink
      English
      arrow-up
      9
      ·
      1 year ago

      Note that this is simply because this study looked at differences for up to a week. Other studies suggest there is a more sustained effect, although it’s not permanent. Antidepressants aren’t permanent either. The argument is to get insurance to cover ketamine since it is a promising treatment for suicidal ideation (and some are starting to cover it).

      • intensely_human@lemm.ee
        link
        fedilink
        English
        arrow-up
        2
        ·
        1 year ago

        I have read, from ketamine infusion recipients, that it was amazing at first but then their depression got worse after the initial period of relief.

        That’s the reason I haven’t done it myself. People who have enough money to keep getting the infusions swear by it. But people who don’t have some very disturbing stories to tell.

        • ickplant@lemmy.worldOP
          link
          fedilink
          English
          arrow-up
          1
          ·
          1 year ago

          That’s interesting, I’ve also heard the opposite, and I think this just shows we need way more research - and of course way more coverage by insurance. I also wonder if people who got worse had just depression or depression and PTSD. I have a personal pet theory about that (basically, I’m curious whether, if you have PTSD the infusions will make you better short-term, but you still need therapy to process the trauma to receive long-term relief - no actual research support for this yet).

      • Tolstoshev@lemmy.world
        link
        fedilink
        English
        arrow-up
        7
        ·
        1 year ago

        About $300 per session. The ketamine itself is cheap, the doctor’s time is what you’re paying for.

        • Obi@sopuli.xyz
          link
          fedilink
          English
          arrow-up
          4
          ·
          1 year ago

          Was gonna say, I don’t remember ket being that expensive through the, err, unregular channels. Then again I’m not in America this would just be free here.

            • Obi@sopuli.xyz
              link
              fedilink
              English
              arrow-up
              2
              ·
              1 year ago

              Not sure what you mean with infusion, I assumed IV meant intra-venous, which, yeah some folks do that unfortunately, though now that I think about it I think it would mostly be done intra-muscular (in a muscle rather than a vein).

              • intensely_human@lemm.ee
                link
                fedilink
                English
                arrow-up
                2
                ·
                1 year ago

                You’re saying it would be free in your country. I’m saying that this is already a practice so my question is do people already do it there and is it already free there?

                • Obi@sopuli.xyz
                  link
                  fedilink
                  English
                  arrow-up
                  1
                  ·
                  1 year ago

                  Oh right, gotcha. No I have no idea if it’s done sorry, I only have information about the illegal use of it…