In this video, Dr. Bret Scher shares the latest clinical data on ketogenic therapy for depression, including two new studies showing meaningful improvements, even remission, in people with moderate to severe symptoms. For individuals struggling with treatment-resistant depression, these findings offer real hope and open the door to a new therapeutic pathway: metabolic interventions that target brain energy.
-
A pilot study examining a ketogenic diet as an adjunct therapy in college students with major depressive disorder https://doi.org/10.1038/s41398-025-03544-8
-
Medically supervised ketogenic diet as an adjunctive treatment for moderate to severe depression: A pilot study https://doi.org/10.1016/j.jad.2025.121079
-
Keto For College Depression Blog https://www.metabolicmind.org/resources/library/blog/perspectives-in-metabolic-psychiatry/new-research-a-ketogenic-diet-improved-depression-in-college-students
-
Depression Topic Page https://www.metabolicmind.org/resources/topics/keto-for-depression
Having read the top two papers, they key seems to actually track ketones in the study group, self moderating compliance has a huge impact on outcomes.