Judging by the stories I have heard about Greyhound, the Benadryl is a very nice gesture. That way, the people who steal your kidneys will have to spend less on drugs for you.

Im with you. I did this from TX to PA in the late 90s and would not recommend. I had it both ways though - a friend on the ride up who was moving there. The ride home alone was indeed that much more long and depressing. 1/2 star would not recommend

If you ever have to do this buy yourself lots of benadryl and just sleep as much as possible.

Err, nah fuck that; https://en.m.wikipedia.org/wiki/Killing_of_Tim_McLean#:~:text=On 30 July 2008%2C Tim,of Portage la Prairie%2C Manitoba.

According to witnesses, McLean was sleeping with his headphones on when the man sitting next to him suddenly produced a large knife and began stabbing him in the neck and chest. After the attack began, the bus driver pulled to the side of the road, and he and all the other passengers fled the vehicle. The driver and two other men made an attempt to rescue McLean, but were chased away by Li, who slashed at them from behind the locked bus doors. Li ultimately decapitated McLean and displayed his severed head to those standing outside the bus, then returned to McLean’s body and began severing other parts and consuming some of McLean’s flesh.