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kixik@lemmy.ml to Science@lemmy.ml · 2 years ago

90% Reduction: Scientists Discover Natural Molecule That Eradicates Plaques and Cavities

scitechdaily.com

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90% Reduction: Scientists Discover Natural Molecule That Eradicates Plaques and Cavities

scitechdaily.com

kixik@lemmy.ml to Science@lemmy.ml · 2 years ago
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3,3′-Diindolylmethane (DIM) decreased the Streptococcus mutans biofilm, a leading contributor to plaque and cavities, by 90%. A significant portion of the global population experiences persistent issues with dental plaque and cavities or will face them at some time. While toothpaste, mouthwash, and

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  • DarthBueller@lemmy.world
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    2 years ago

    You know how they seal kids teeth, and insurance covers it? It basically keeps kids from getting cavities until the sealant eventually wears off. Well, they could put the same sealant on adults. But they don’t.

    • Mothra@mander.xyz
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      I’ve lived in at least two places where that treatment is available for adults. Insurance may cover it depending on what kind of insurance you got, it is expensive but not ridiculously so in comparison to other dental procedures.

    • MonkderZweite@feddit.ch
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      Uh, no, i don’t. Sounds weird, where do they do this?

      • DarthBueller@lemmy.world
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        I had it done in the USA in the 90s when I had my adult teeth, not sure if it was before or after I got my 12 year molars. I asked about it a few years ago and the dentist said that insurance only covers it for kids.

        • MonkderZweite@feddit.ch
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          What do they use for sealing? I’m swiss and we don’t do this. Is it because you have corn sirup everywhere?

          edit: so, uh, is this widespread?

          • Lokoschade@feddit.de
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            2 years ago

            I’m German and this is definitely also done here

          • DarthBueller@lemmy.world
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            2 years ago

            I have no idea. It’s white and it cures hard with exposure to UV light. It might just be filling media used as a surface sealant—not a dentist, sorry.

      • Turun@feddit.de
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        2 years ago

        Germany.

      • Alytastic@lemmy.one
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        Almost all children in USA get sealants as a preventative measure, in my experience.

    • bluebooby@lemmy.world
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      My wife works in dental insurance so I asked her. She said for the general public, the effectiveness of the sealant decreases as the client ages, because an adult’s tooth is more smooth than a child’s. So there’s a critical age where the cons outweighs the pros.

      • Piecemakers@lemmy.world
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        If you think that the entire dental industry is fully prepared and willing to negate billions of dollars in profit per year but the porosity of adult teeth has simply tied their hands… I’ve got a couple bridges to sell you.

        • kephalos@discuss.tchncs.de
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          I am 38 and have so far had no cavity. Turns out adults have a very easy handle on dental hygiene, brushing your teeth, flossing and avoiding candy and sweet drinks

    • Big P@feddit.uk
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      2 years ago

      They do that?

      • DarthBueller@lemmy.world
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        Yes. It covers the top of the teeth kids still need to brush really well because you can easily get cavities in between your teeth, etc…

        • robbotlove@lemmy.world
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          2 years ago

          is that the mouthgaurd filled with flavored goo that you have to keep in your mouth for 29 minutes while you drool all over yourself?

          • Talaraine@kbin.social
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            That’s flouride. https://asantedental.ca/blog/dental-fluoride-include-part-oral-routine/

            • Fuck_u_spez_@lemmy.world
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              And you’re basically supposed to do the same thing twice a day with your toothpaste, which is why the tube says “spit out after brushing” and not “make a little cup with your hand and use it to swish some water from the sink around in your mouth, rinsing most of the fluoride off before it has a chance to work”.

              • LibertyLizard@slrpnk.net
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                But it tastes so bad…

                • gregorum@lemm.eeBanned from community
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                  Buy better tasting toothpaste

                • Fuck_u_spez_@lemmy.world
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                  deleted by creator

    • Alytastic@lemmy.one
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      One of the reasons we don’t seal adult teeth is because insurance doesn’t cover it and people don’t want to pay for it (there are other reasons like prior fillings, loss of tooth structure, groove being less prominent, etc). If someone asks for it to be done and agrees to pay out of pocket we’ll definitely do it.

    • dalekcaan@lemm.ee
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      I’ve had it done as a young adult. Fluoride treatments too. Maybe my dentist is weird, but some places definitely do it.

  • chemicalprophet@lemm.ee
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    I was curious about which compound and where it occurs, the article didn’t contain the latter. This is the compound’s Wikipedia article which provides that info: https://en.m.wikipedia.org/wiki/3,3’-Diindolylmethane

    • ogeist@lemmy.dbzer0.com
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      found in cruciferous vegetables, such as broccoli, Brussels sprouts, cabbage and kale.

      That explains a lot

      • chemicalprophet@lemm.ee
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        Oui chef! I also found that its already being sold as a dietary supplement interesting.

      • bermuda@beehaw.org
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        Brb about to empty the shelves of broccoli. Both pre chopped AND whole

        • zout@kbin.social
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          The molecule is formed during the digestion of broccoli, so unless you’re gonna put your digested broccoli back into your mouth it probably won’t have the desired effect.

          • Killing_Spark@feddit.de
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            Wait, we don’t all partake in resnacking?

            • randomsnark@lemmy.ml
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              2 years ago

              Bulimia - twice the taste, and no calories!

            • gregorum@lemm.eeBanned from community
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              2 years ago

              Moo!

              • Killing_Spark@feddit.de
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                2 years ago

                You know what? I like you.

                • gregorum@lemm.eeBanned from community
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                  I like moo, too! We can be cuddies!

          • LennethBright@artemis.camp
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            Looks like cows were onto something with the whole swallow and then rechew mechanic.

          • JanoRis@kbin.social
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            So it seems that during the digestion in stomach acid the enzyme myrosinase is released from these plants (https://www.diindolylmethane-dim.com/formation.htm) responsible for the intermediate product DIM.

            This means we could have DIM present in acidic meals of these vegetables, like for example Kimchi

        • Kalkaline@programming.dev
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          deleted by creator

          • TubeTalkerX@kbin.social
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            Choppin’ broccoli

            • Ben Hur Horse Race@lemm.ee
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              2 years ago

              she chop, she chop, she chop, she chop, ahhooough

              • ivanafterall@kbin.social
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                2 years ago

                My childhood just came flooding back.

      • Evilsandwichman [none/use name]@hexbear.net
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        There are several cruciferous vegetables I’d like to have as snacks now that I’m dieting but unfortunately as I read about it, too much cruciferous vegetables can cause health issues (bad enough that too much of unhealthy stuff can cause issues, but it turns out even the healthy stuff can cause issues (specifically thyroid related) if you have too much; you just can’t win!)

      • FlumPHP@programming.dev
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        If I’m reading this right, it’s a digested form of something else in those vegetables. So adding broccoli to toothpaste isn’t going to cut it. (Although I’m sure some brand on IG is already manufacturing that)

      • gregorum@lemm.eeBanned from community
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        Even a 90% chance of a reduction in cavities and plaque could not get me to eat kale.

  • Send_me_nude_girls@feddit.de
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    Diindolylmethane might act like estrogen in the body, or might also block estrogen effects. So more research is necessary.

    • Che Banana@lemmy.ml
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      I will sacrifice myself and get titties as long as I have good teeth!

      edit who am I kidding, I already have removedtiddies

      • Vlyn@lemmy.zip
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        You ran right into the slur filter of lemmy.ml :)

        • Jay@lemmy.ca
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          ahh that makes sense now… I was wondering wtf are removedtitties. I thought they were talking about a mastectomy or something.

        • Turun@feddit.de
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          I don’t get what it’s supposed to be. Can you spell it out for me with a between every letter or something to defeat the filter?

          • Vlyn@lemmy.zip
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            I’m not the guy who wrote it, but if I had to guess he probably meant bi.tchtiddies?

            The slur filter on lemmy.ml is weird, that’s why I changed instances.

            • Turun@feddit.de
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              My first instinct was mantiddies, it makes sense with the “I’d grow a pair if it means healthier teeth”. But it would be an absurd word to filter.

        • Maldreamer141@lemmy.ml
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          Ahh just discovered ml has a slur filter few mins back

      • Twipped@artemis.camp
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        DIM doesn’t increase estrogen, it reduces it. It forces the body to metabolize estradiol into 2-hydroxyestrone, which cannot be converted back to estradiol and has lower binding affinity, so it just gets pissed out. It’s often used for breast and thyroid cancer treatments.

        So yeah, this could be really bad for women.

      • db2@lemmy.world
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        2 years ago

        Robert Paulson, is that you?

      • yabai@lemmy.world
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        2 years ago

        Do you have an alt on lemmynsfw.com?

  • PlatypusXray@feddit.de
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    It’s amazing what mankind has achieved in vitro.

    • Dr Cog@mander.xyz
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      https://xkcd.com/1217/

      • PlatypusXray@feddit.de
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        Thanks, couldn’t find it.

    • lavadrop@lemmy.ml
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      OMG I choked so hard!

  • doublejay1999@lemmy.world
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    It’s 2023, how they ain’t got pills make your teeth grow back ??

    • twelvefloatinghands@lemmy.world
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      Is pill. Goes past teeth.

    • Touching_Grass@lemmy.world
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      Same with skin dermatology type conditions. How they fuck do we not have a pill or cream to cure itchy scalp. Why do I need to use expensive shampoos every two days the rest of my life or else I scratch my dandruffy scalp until it bleeds because there’s some fungus I now have to deal with until my immune system gets so old that the fungus takes over

    • BeigeAgenda@lemmy.ca
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      It’s not long ago I saw a article about regrowth of theeth, but it was not a pill.

    • Mindlight@lemmy.world
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      We do but Illuminati made sure it’s only available to about 1% of the population…

      • TheDarkKnight@lemmy.world
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        So that’s how Elon and Lebron got their hairback???!

    • electrogamerman@lemmy.world
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      Id rather have a pill that makes my dick grow more

    • DireLlama@ttrpg.network
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      I read an article about that. IIRC it’s mainly because there is only minimal bloodflow in your teeth - barely enough to supply it with nutrients (and still not enough you should skip external flouride etc.).

  • Tylerdurdon@lemmy.world
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    How long until dentists call it fake?

    • babyphatman @lemmy.ml
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      You sound like an anti-dentite!

      • Teon@kbin.social
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        I think his name is Al. Al Dentay.

      • tacosplease@lemmy.world
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        Finally found the 1 out of 5 dentists that doesn’t recommend chewing Trident gum.

    • mihor@lemmy.ml
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      The Big Denta.

  • Assian_Candor [comrade/them]@hexbear.net
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    Dead bio-volumes in all dosages were not detected, eliminating the possibility of antimicrobial activity elicited by DIM treatment.

    From the paper. Interesting it’s NOT an antibiotic but just inhibits biofilm formation. The paper also alludes to an anti-acne application.

    This is very cool. Thanks for sharing!

  • The dogspaw @midwest.social
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    I did not need to see that gross picture today thanks for nightmare fuel

    • dontcarebear@lemmy.ml
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      deleted by creator

      • The dogspaw @midwest.social
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        I don’t know what that means but them teeth are ewe

        • Piecemakers@lemmy.world
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          Those are not sheep teeth.

  • Yerbouti@lemmy.ml
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    Mmmkay, but what about tooth decay, mmkay?

    • nutlink@beehaw.org
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      deleted by creator

    • Umbrias@beehaw.org
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      Not much to do about a decayed tooth short of stem cells so not sure why you’re asking about repair for something that’s entirely preventative

      • emptiestplace@lemmy.ml
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        Is this the most intellectually dishonest thing you were able to come up with on short notice?

        • Umbrias@beehaw.org
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          No. That’s… Not what intellectual dishonesty is.

          • emptiestplace@lemmy.ml
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            So you actually believe that was a reasonable question?

            • Umbrias@beehaw.org
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              Why isn’t it?

              • emptiestplace@lemmy.ml
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                It’s like asking someone why they care about advances in other types of remedial care like bypass surgery or whatever.

                • Umbrias@beehaw.org
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                  What lmao. This is so nonsensical I have no response.

      • Aagje_D_Vogel@feddit.nl
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        In case it kidnaps the to-be Queen of Canada.

        • Umbrias@beehaw.org
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          Of course.

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