Personally haven’t used Infuse so this may not be entirely useful.

Big factors keeping me on Plex:

• Native clients available for almost every device (PS4, XB1, Smart TVs, you name it they probably have it)
• Plexamp
• Things like playlists, which while I can export from the sqlite DB if I really want to go, it would be a hassle to
• Linux HTPC app

Less important factors:

• Live TV (from Plex, not a HDHomerun etc) useful for background noise
• ‘Discover’ feature allowing me to see what latest movies are out 🚢⛵🧲
• Very easy to share content with others
• Casting to other devices in the home

Well, Plex is a media server 1st and foremost. I’ve never heard of Infuse before, so I did a search and from what I read it is just an iOS media player that can pull from multiple servers (including Plex.) So, I use Plex to manage all of my media and they have native apps for pretty much everywhere including smart TV’s, Andriod, iPhone, Windows, Linux, Mac, gaming systems, and a web player. I am currently looking into FOSS alternatives, but for the past 10 years Plex has been the best for my needs.